COMPOSITION
MMR (Measles, Mumps and Rubella Vaccine (Live) I.P.) freeze-dried is prepared from live attenuated strains of Edmonston-Zagreb Measles virus propagated on human diploid cell culture, L-Zagreb Mumps virus propagated on chick embr fibroblast cells and Wistar RA 27/3 Rubella virus propagated on human diploid cell culture. The reconstituted vaccine contains, in single dose of 0.5 ml not less than mmr vaccine in hyderabad,typhoid vaccine in hyderabad,yellow fever vaccine in india,polio vaccines.
MMR (Measles, Mumps and Rubella Vaccine (Live) I.P.) freeze-dried is prepared from live attenuated strains of Edmonston-Zagreb Measles virus propagated on human diploid cell culture, L-Zagreb Mumps virus propagated on chick embr fibroblast cells and Wistar RA 27/3 Rubella virus propagated on human diploid cell culture. The reconstituted vaccine contains, in single dose of 0.5 ml not less than mmr vaccine in hyderabad,typhoid vaccine in hyderabad,yellow fever vaccine in india,polio vaccines.
INDICATIONS
TRESIVAC is indicated for active immunization in children of 12 months to 10 years of age against Measles, Mumps and Rubella infections simultaneously. For Immunisation of children above 10 years and suscebtible nonpregnant adult individuals, we recommend to use MR-VAC (Measles and Rubella Vaccine) (Rubella vaccine) while observing certain precautions as indicated under the heading contraindications.
MMR vaccine can also be given to adults at any age in case they have missed the vaccination in childhood and or there is no vaccination record available, by giving 2 doses of MMR with an interval of minimum 4 weeks. However, it is important to note that vaccination in adults can cause higher percentage of adverse reactions as compared to childhood vaccination. Amongst these the commonly encountered side reactions are unilateral or bilateral parotitis and fever. To avoid such reactions, if the physician desires, MR vaccine can be recommended instead of MMR vaccine. MMR vaccine can be safely and effectively given simultaneously with DTP, DT, TT, Td, BCG, Polio vaccine (OPV and IPV), Haemophilus influenzae type b, Hepatitis B, Yellow fever vaccine and vitamin A supplementation.
TRESIVAC is indicated for active immunization in children of 12 months to 10 years of age against Measles, Mumps and Rubella infections simultaneously. For Immunisation of children above 10 years and suscebtible nonpregnant adult individuals, we recommend to use MR-VAC (Measles and Rubella Vaccine) (Rubella vaccine) while observing certain precautions as indicated under the heading contraindications.
MMR vaccine can also be given to adults at any age in case they have missed the vaccination in childhood and or there is no vaccination record available, by giving 2 doses of MMR with an interval of minimum 4 weeks. However, it is important to note that vaccination in adults can cause higher percentage of adverse reactions as compared to childhood vaccination. Amongst these the commonly encountered side reactions are unilateral or bilateral parotitis and fever. To avoid such reactions, if the physician desires, MR vaccine can be recommended instead of MMR vaccine. MMR vaccine can be safely and effectively given simultaneously with DTP, DT, TT, Td, BCG, Polio vaccine (OPV and IPV), Haemophilus influenzae type b, Hepatitis B, Yellow fever vaccine and vitamin A supplementation.
AND DOSAGE AND ADMINISTRATION
The vaccine should be reconstituted with the entire contents of the diluent supplied (Sterile water for injections) using a sterile syringe and needle. With gentle shaking the dried cake is easily dissolved. After reconstitution the vaccine should be used immediately. A single dose of 0.5 ml should be administered by deep subcutaneous injection into the anterolateral aspect of upper thigh in toddlers and upper arm in older children. If the vaccine is not used immediately then it should be stored in the dark at 2° - 8°C for no longer than 6 hours.
The diluent and reconstituted vaccine should be inspected visually for any foreign particulate matter and / or variation of physical aspects prior to administration. In the event of either being observed, discard the diluent or reconstituted vaccine.
The vaccine should be reconstituted with the entire contents of the diluent supplied (Sterile water for injections) using a sterile syringe and needle. With gentle shaking the dried cake is easily dissolved. After reconstitution the vaccine should be used immediately. A single dose of 0.5 ml should be administered by deep subcutaneous injection into the anterolateral aspect of upper thigh in toddlers and upper arm in older children. If the vaccine is not used immediately then it should be stored in the dark at 2° - 8°C for no longer than 6 hours.
The diluent and reconstituted vaccine should be inspected visually for any foreign particulate matter and / or variation of physical aspects prior to administration. In the event of either being observed, discard the diluent or reconstituted vaccine.
REACTIONS ADVERSE
The type and rate of severe adverse reactions do
not differ significantly from the measles, mumps and rubella vaccine reactions
described separately.The measles vaccine may cause within 24 hours of vaccination mild pain and tenderness at the injection site. In most cases, they spontaneously resolve within two to three days without further medical attention. A mild fever can occur in 5-15% of vaccinees 7 to 12 days after vaccination and last for 1-2 days.
Rash occurs in approximately 2% of recipients, usually starting 7-10 days after vaccination and lasting 2 days. The mild side effects occur less frequently after the second dose of a measles-containing vaccine and tend to occur only in person not protected by the first dose. Encephalitis has been reported following measles vaccination at a frequency of approximately one case per
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