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What do we really know about the 2009 H1N1 swine flu vaccine? What do we really not know?

Questions about the safety of the vaccine persist. Surf the Internet or flip through TV stations and you'll encounter a multitude of myths and a whole lot of hype

What are the facts? Straightforward answers follow these questions:

·         Is the 2009 H1N1 swine flu vaccine safe?

·         Isn't the 2009 H1N1 swine flu vaccine too new to trust?

·         Why should I believe what government scientists say about swine flu?

·         Does the H1N1 swine flu vaccine contain thimerosal?

·         The 1976 swine flu vaccine wasn't safe. Why should I trust this one?

·         Do we really know what drugmakers are putting in the swine flu vaccine?

H1N1 swine flu vaccine safe?

No vaccine is 100% safe for everyone. People with allergies to eggs, for example, can't take flu vaccines because eggs are involved in the manufacturing process.

And flu vaccines cause mild but common reactions. About one in three people get a sore arm from the shot, some with a little redness or even swelling. Some 10% to 15% of people feel tired or get a headache; some may even run a low fever.

And vaccines can trigger rare but serious reactions, even among people with no apparent allergies or sensitivities.

So if vaccines aren't 100% safe, why risk them?

Approved vaccines -- including the 2009 H1N1 swine flu vaccine -- are calculated to be much, much less risky than the diseases they prevent. For example, out of every million people who get a flu shot, one or two will get a serious neurological reaction called Guillain-Barre syndrome (GBS).

But flu itself causes serious problems, including GBS, in far more than two in a million cases. And since a large proportion of the population will get swine flu, the vaccine risk is far smaller than the disease risk.

In clinical trials, 10,000 to 15,000 children and adults have received various manufacturers' brands of H1N1 swine flu vaccine. Nothing serious happened to any of them, including this reporter, who received a double dose of the Sanofi-Pasteur swine flu vaccine.